4/8/2023 0 Comments Calex 6255 calibrationPrecision of merit was 98.05% and 99.03% with respect to two readings. The mean diameter error between automated and two manual readings was 0.27 ± 0.26 and 0.26 ± 0.28 mm, respectively. The coefficient of correlation between automated and two manual readings was 0.91 and 0.92. Two trained neuro radiologists performed manual lumen border tracings using ImgTracerTM software. Results.-Our database consists of institutional review board–approved 202 patients (males/females: 155/47) left and right common carotid artery images (404 images, Toshiba scanner). This clinical system outputs lumen diameter along with stenosis severity index (SSI). Using global and local processing, lumen boundaries are detected. Stage two uses lumen pixel region identification based on the assumption that blood flow has constant density. Stage one uses spectral analysis based on the hypothesis that far-wall adventitia is brightest. Methods.-This article presents AtheroEdgeTM 2.0, a two-stage process for automated carotid lumen diameter measurement that combats the above challenges. Image-based methods face a challenge because of low gradients in media and intima walls. Systolic velocity-based methods for lumen diameter and stenosis measurement are subjective. Objective.-Degree of carotid stenosis is an important predictor to assess risk of stroke.
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